Meyer E, Ludatscher R M, Zonis S
Br J Ophthalmol. 1984 Jun;68(6):416-20. doi: 10.1136/bjo.68.6.416.
Biopsy material from primary and secondary overacting inferior oblique muscles were examined by light and electron microscopy. Most muscle fibres were in different stages of atrophy. A high variation of alterations was encountered in all muscles. The most striking abnormalities were huge accumulations of mitochondria and muscle vacuolisation related mainly to the enlargement of the tubules of sarcoplasmic reticulum. The mitochondrial aggregates and vacuolisation occupied more muscle surface in the inferior muscles of primary overaction than those of secondary overaction.
对原发性和继发性上斜肌亢进的活检材料进行了光镜和电镜检查。大多数肌纤维处于不同程度的萎缩阶段。所有肌肉均出现高度变异的改变。最显著的异常是线粒体大量聚集以及肌肉空泡化，主要与肌浆网小管扩张有关。原发性上斜肌亢进下斜肌中的线粒体聚集和空泡化比继发性上斜肌亢进下斜肌占据更多的肌肉表面。
