Rerat A A, Vaissade P, Vaugelade P
Br J Nutr. 1984 May;51(3):505-15. doi: 10.1079/bjn19840056.
Concentrations of reducing sugars, glucose, fructose and lactic acid in blood obtained from arterial and portal catheters were measured for periods of 8-24 h in twenty-three unanaesthetized pigs (mean body-weight 50 kg). From 6 to 8 d after implantation of catheters, the animals received experimental meals containing different levels (400, 800, 1200, 1600 g respectively) of different sugars (glucose ten meals, sucrose eighteen meals, lactose nine meals, maize starch sixteen meals) as well as a protein-mineral-vitamin premix. After each meal the reducing sugars appeared in the portal blood in successive waves. The porto-arterial differences in the concentration of reducing sugars, representing the real appearance of sugar-hydrolysis products in the animal, varied greatly according to the sugar ingested and its level of intake. For each level of intake, these differences were larger, but of shorter duration, for glucose and sucrose than for maize starch. For these three carbohydrates, the higher the level of ingestion, the larger and the more persistent the porto-arterial differences. Lactose represented a special case, as the porto-arterial differences of reducing sugars were always much lower than those obtained with the other sugars and they did not vary with the level of intake. Our findings show that the products formed by feeding glucose and sucrose appear more rapidly in the portal blood than those formed by feeding lactose. Accordingly, the length of time of digestion of glucose and sucrose is shorter than that of maize starch and lactose.
在23头未麻醉的猪（平均体重50千克）身上，通过动脉和门静脉导管采集血液，测量其中还原糖、葡萄糖、果糖和乳酸的浓度，测量时间为8至24小时。在植入导管后的6至8天，给这些动物喂食含有不同水平（分别为400、800、1200、1600克）不同糖类（葡萄糖10次喂食、蔗糖18次喂食、乳糖9次喂食、玉米淀粉16次喂食）以及蛋白质 - 矿物质 - 维生素预混料的实验餐。每餐之后，还原糖在门静脉血液中呈连续波状出现。还原糖浓度的门静脉 - 动脉差异代表了动物体内糖水解产物的实际出现情况，根据摄入的糖类及其摄入量水平的不同而有很大差异。对于每种摄入量水平，葡萄糖和蔗糖的这些差异更大，但持续时间更短，相比玉米淀粉而言。对于这三种碳水化合物，摄入水平越高，门静脉 - 动脉差异就越大且持续时间越长。乳糖是个特殊情况，因为还原糖的门静脉 - 动脉差异总是远低于其他糖类，并且不随摄入量水平而变化。我们的研究结果表明，喂食葡萄糖和蔗糖形成的产物在门静脉血液中出现得比喂食乳糖形成的产物更快。因此，葡萄糖和蔗糖的消化时间比玉米淀粉和乳糖的消化时间短。
