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[一种通过双层脂质膜的非电生性阳离子转运模型]

[A model of non-electrogenic cation transport through bilayer lipid membranes].

作者信息

Antonenko Iu N, Iaguzhinskiĭ L S

出版信息

Biofizika. 1984 Mar-Apr;29(2):232-6.

PMID:6722193
Abstract

Quantitative relationship between the proton diffusion potential in the unstirred layers near BLM and NH4Cl was investigated. It has been found that in the range of low concentrations of NH4Cl the potential value depends on the difference of salt concentrations on different sides of the membrane. At higher concentrations the potential value is the function of the ratio of salt concentrations at different BLM sides. In the limiting case the potential value equals 58 mV with NH4Cl concentrations ratio equaling ten. A model is suggested which quantitatively describes the experimental data. It has been shown that the results obtained can be used in determining BLM permeability for weak acids and bases.

摘要

研究了BLM附近未搅拌层中质子扩散电位与NH4Cl之间的定量关系。已发现,在NH4Cl低浓度范围内,电位值取决于膜两侧盐浓度的差异。在较高浓度下,电位值是膜两侧不同盐浓度比值的函数。在极限情况下,当NH4Cl浓度比等于10时,电位值等于58 mV。提出了一个定量描述实验数据的模型。结果表明,所获得的结果可用于确定BLM对弱酸和弱碱的渗透性。

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