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[臭氧对平面双层脂质膜通透性的影响]

[Effect of ozone on the permeability of flat bilayer lipid membranes].

作者信息

Semenkova G N, Kedits G, Cherenkevich S N, Khmel'nitskiĭ A I

出版信息

Biofizika. 1984 Mar-Apr;29(2):323-5.

PMID:6722202
Abstract

The influence of the liposome ozonolysis products on ionic permeability and stability of the planar bilayer lipid membrane ( PBLM ) was studied by electroconductivity . Addition of ozonized liposomes and PBLM preparation from the products of the ozonized lipids results in a decrease of the PBLM resistance. It is suggested that the enhancement of PBLM stability from ozonized lipids may be caused by production during lipid peroxidation of the intermolecular bonds between lipid molecules and by an increase of the lipid bilayer rigidity.

摘要

通过电导率研究了脂质体臭氧分解产物对平面双层脂质膜(PBLM)离子通透性和稳定性的影响。添加经臭氧处理的脂质体以及用经臭氧处理的脂质产物制备PBLM会导致PBLM电阻降低。有人认为,经臭氧处理的脂质增强PBLM稳定性可能是由于脂质过氧化过程中脂质分子间形成分子间键以及脂质双层刚性增加所致。

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