McGarvey K A, Lee J M, Boughner D R
Biomaterials. 1984 Mar;5(2):109-17. doi: 10.1016/0142-9612(84)90011-5.
We have examined the tensile viscoelastic properties of fresh and glycerol-preserved human dura mater, and correlated the results with structural information from the scanning electron microscope. The interwoven laminar structure of dura produces rather high flexural stiffness, while the crossed-fibrillar laminae produce planar mechanical isotropy. Glycerol storage shifts the stress-strain curve to lower strain, reduces stress relaxation and creep, and lowers the ultimate tensile strength and strain at fracture. These changes may be due to glyceraldehyde crosslinking, or to increased interfibrillar friction. The latter hypothesis suggests that glycerol storage may reduce the fatigue lifetime of the tissue.
我们研究了新鲜的和经甘油保存的人类硬脑膜的拉伸粘弹性特性，并将结果与扫描电子显微镜获得的结构信息相关联。硬脑膜的交织层状结构产生相当高的弯曲刚度，而交叉纤维层产生平面力学各向同性。甘油储存使应力-应变曲线向较低应变方向移动，降低应力松弛和蠕变，并降低极限拉伸强度和断裂应变。这些变化可能是由于甘油醛交联，或由于纤维间摩擦增加。后一种假设表明，甘油储存可能会缩短组织的疲劳寿命。
