Irle E, Markowitsch H J
Brain Res Bull. 1984 Mar;12(3):283-93. doi: 10.1016/0361-9230(84)90056-x.
Efferent projections from the basal forebrain to the prefrontal cortex of the lesser bush baby (Galago senegalensis) were traced with the retrograde horseradish peroxidase technique. Different areas of the prefrontal cortex of six bush babies were injected with small amounts of horseradish peroxidase. The entire basal forebrain was then screened for labeled neurons. Following all six injections, many retrogradely labeled neurons could be detected in the nucleus basalis of Meynert. These results indicate a strong innervation of the bush baby's prefrontal cortex by the nucleus basalis of Meynert. The observed projections seem comparable in strength and topography to those found in another primate species, the rhesus monkey. Anatomical and functional implications of these projections in the bush baby are discussed and related to findings in other primates and species of other orders.
采用逆行辣根过氧化物酶技术追踪了塞内加尔婴猴(Galago senegalensis)基底前脑到前额叶皮质的传出投射。对6只婴猴的前额叶皮质不同区域注射少量辣根过氧化物酶。然后对整个基底前脑进行标记神经元筛查。在所有6次注射后,可在迈内特基底核中检测到许多逆行标记的神经元。这些结果表明迈内特基底核对婴猴前额叶皮质有强烈的神经支配。观察到的投射在强度和拓扑结构上似乎与在另一种灵长类动物恒河猴中发现的投射相当。讨论了这些投射在婴猴中的解剖学和功能意义,并与其他灵长类动物和其他目物种的研究结果相关联。