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过氧化氢作为一种局部止血剂。

Hydrogen peroxide as a topical hemostatic agent.

作者信息

Hankin F M, Campbell S E, Goldstein S A, Matthews L S

出版信息

Clin Orthop Relat Res. 1984 Jun(186):244-8.

PMID:6723153
Abstract

Many research efforts have been directed toward enhancing the bone-cement interface of total joint arthroplasties. Hemostatic agents have been popularized as effective means of retarding the development of potentially harmful debris interposition adjacent to, and blood lamination patterns within, the methylmethacrylate. The hemostatic effectiveness of hydrogen peroxide was tested on six metaphyseal bone beds in ten mongrel dogs: three sites were treated with hydrogen peroxide and three were saline-treated control sites. The hemostatic effect of the treatments was determined by comparing blood loss per unit area per minute before and after application of the test solutions. The results indicate that hydrogen peroxide is an effective hemostatic agent and reduces the amount of blood and debris trapped within the trabecular bone methylmethacrylate interface.

摘要

许多研究工作都致力于增强全关节置换术中骨水泥界面。止血剂已被广泛应用,作为延缓甲基丙烯酸甲酯附近潜在有害碎片插入以及其内部血液分层模式发展的有效手段。在十只杂种狗的六个干骺端骨床测试了过氧化氢的止血效果:三个部位用过氧化氢处理,三个部位用生理盐水处理作为对照部位。通过比较测试溶液应用前后每分钟单位面积的失血量来确定处理的止血效果。结果表明,过氧化氢是一种有效的止血剂,可减少被困在小梁骨甲基丙烯酸甲酯界面内的血液和碎片量。

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