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髋部骨折死亡率。与年龄、治疗、术前疾病、手术时间及并发症的关系。

Hip fracture mortality. Relation to age, treatment, preoperative illness, time of surgery, and complications.

作者信息

Kenzora J E, McCarthy R E, Lowell J D, Sledge C B

出版信息

Clin Orthop Relat Res. 1984 Jun(186):45-56.

PMID:6723159
Abstract

This retrospective analysis of 406 patients with proximal femoral fractures was designed to identify both the significant and nonsignificant risk factors that influence patient mortality. The 399 patients treated by open reduction and internal fixation or femoral head prostheses routinely received prophylactic antibiotics and anticoagulants. Of 406 patients followed until death or for at least one year, the overall mortality rate at one year was 14% (58/406). For patients with subcapital fractures the rate was 13% (25/187) and with intertrochanteric fractures 15% (33/219). The expected mortality rate for the normal population of similar age was about 9%. Sex, treatment of subcapital fracture by either internal fixation or arthroplasty, and the level of postoperative ambulation did not influence mortality. The number of preexisting medical conditions and the time of surgery following admission were highly significant factors (p less than or equal to 0.001 for both). The number of postoperative medical complications was also significant. The recommendation is for serious medical conditions to be maximally stabilized for at least 24 hours and pulmonary and physical therapy instituted before scheduling open surgical procedures.

摘要

这项对406例股骨近端骨折患者的回顾性分析旨在确定影响患者死亡率的显著和非显著风险因素。399例行切开复位内固定术或股骨头假体置换术的患者常规接受预防性抗生素和抗凝剂治疗。在406例随访至死亡或至少一年的患者中,一年时的总死亡率为14%(58/406)。对于股骨头下骨折患者,死亡率为13%(25/187),转子间骨折患者为15%(33/219)。相似年龄正常人群的预期死亡率约为9%。性别、股骨头下骨折采用内固定术还是关节置换术治疗以及术后活动水平均不影响死亡率。术前存在的内科疾病数量和入院后手术时间是高度显著的因素(两者p均≤0.001)。术后内科并发症的数量也具有显著性。建议在安排开放手术前,将严重内科疾病尽可能稳定至少24小时,并开展肺部和物理治疗。

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