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与老年髋部骨折患者 30 天死亡率相关的预测因素。

Predictive factors associated with thirty-day mortality in geriatric patients with hip fractures.

机构信息

Department of Orthopedics and Traumatology, Osmangazi University, School of Medicine, Eskişehir, Turkey.

出版信息

Acta Orthop Traumatol Turc. 2022 Jul;56(4):240-244. doi: 10.5152/j.aott.2022.21407.

Abstract

OBJECTIVE

This study aimed to determine the predictive factors affecting the 30-day mortality in geriatric hip fractures, investigate the effect of the timing of surgery, and thus determine the optimum cut-off time in delaying the surgery.

METHODS

A total of 596 patients(205 men, 391 women; mean age = 78.3 years) were included in this retrospective study. All possible predictive factors encountered in the literature review, including age, sex, fracture type, comorbidities, American Society of Anesthesiologists (ASA) score, surgical delay time, anaesthesia type, surgery type, need for erythrocyte replacement, postoperative complications, and the need for postoperative intensive care were analyzed. The predictive factors that were found to be significant as a result of the univariate analysis were included in the multivariate logistic regression analysis.

RESULTS

The reason for surgery was an extracapsular fracture in 359 patients (60.2%) and an intracapsular fracture in 237 (39.8%). Arthroplasty was performed in 256 patients (43%), while proximal femoral nails were used in 251 (42.1%), dynamic hips screws in 68 (11.4%), and cannulated screws in 21 (3.5%). 523 (87.8%) of the patients had an ASA score of 1 or 2, and 73 (12.2%) had an ASA score of 3 or 4. General anaesthesia was performed on 35.2% of the patients, while regional anaesthesia was administered to 64.8%. Major complications developed in 42 patients (7%), while minor complications were observed in 143 (24%). The mean surgical delay time was 3.21 days (1-9 days). The ASA score (P <0.001, OR: 56.83, CI: 5.26-2.820), anesthesia type (P = 0.036, OR: 3.225, CI: 0.079-2.264), surgical delay time (P <0.001, OR: 2.006, CI: 1.02-0.372) and major complication (P = 0.002, OR: 6.41, CI: 0.661-3.053) were determined to be predictive factors of 30-day mortality.

CONCLUSION

This study found the median surgical delay time as three days in surviving patients and five days in deceased ones. Thus, a 3-day surgical delay may be acceptable and sufficient for medical optimization and the consensus of the multidisciplinary team.

LEVEL OF EVIDENCE

Level IV, Therapeutic Study.

摘要

目的

本研究旨在确定影响老年髋部骨折 30 天死亡率的预测因素,探讨手术时机的影响,从而确定手术延迟的最佳截止时间。

方法

回顾性分析 596 例患者(男 205 例,女 391 例;平均年龄 78.3 岁)的所有可能的预测因素。包括年龄、性别、骨折类型、合并症、美国麻醉医师协会(ASA)评分、手术延迟时间、麻醉类型、手术类型、红细胞替代需求、术后并发症以及术后重症监护需求。单因素分析发现有统计学意义的预测因素被纳入多因素逻辑回归分析。

结果

手术原因是 359 例(60.2%)患者为关节外骨折,237 例(39.8%)患者为关节内骨折。256 例(43%)患者行关节置换术,251 例(42.1%)患者行股骨近端髓内钉固定术,68 例(11.4%)患者行动力髋螺钉固定术,21 例(3.5%)患者行空心螺钉固定术。523 例(87.8%)患者 ASA 评分为 1 或 2 分,73 例(12.2%)患者 ASA 评分为 3 或 4 分。35.2%的患者接受全身麻醉,64.8%的患者接受区域麻醉。42 例(7%)患者发生严重并发症,143 例(24%)患者发生轻微并发症。平均手术延迟时间为 3.21 天(1-9 天)。ASA 评分(P<0.001,OR:56.83,CI:5.26-2.820)、麻醉类型(P=0.036,OR:3.225,CI:0.079-2.264)、手术延迟时间(P<0.001,OR:2.006,CI:1.02-0.372)和主要并发症(P=0.002,OR:6.41,CI:0.661-3.053)被确定为 30 天死亡率的预测因素。

结论

本研究发现存活患者的中位手术延迟时间为 3 天,死亡患者的中位手术延迟时间为 5 天。因此,3 天的手术延迟可能是可以接受的,足以进行医疗优化和多学科团队的共识。

证据水平

IV 级,治疗研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3508/9612673/50d2cf3c53ad/aott-56-4-240_f001.jpg

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