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[德国西部缺碘地区新生儿的碘排泄与膳食碘供应]

[Iodine excretion and dietary iodine supply in newborn infants in iodine-deficient regions of West Germany].

作者信息

Heidemann P H, Stubbe P, von Reuss K, Schürnbrand P, Larson A, von Petrykowski W

出版信息

Dtsch Med Wochenschr. 1984 May 18;109(20):773-8. doi: 10.1055/s-2008-1069271.

Abstract

Urinary iodine excretion was measured on the fifth day of life in 461 neonates from nine different towns in the Federal Republic of Germany. There was a progressive fall in levels from north to south, with highest values in Hamburg (2.9 micrograms/dl) and lowest in Freiburg (1.2 micrograms/dl). All levels were lower than those of neonates in other countries in which iodine is added to salt: Stockholm (61 neonates) 9.6 micrograms/dl, Zurich (63) 4.75 micrograms/dl. Iodine analysis of mothers in G ottingen on the fifth day post-partum indicated that iodine excretion in urine of mothers with goitre (51 cases) was significantly lower than in a control group without goitre (38): 17.6 compared with 30.0 micrograms/g creatinine, and the iodine content of breast milk in the goitre group was significantly lower than that of the control group (1.75 compared with 2.5 micrograms/dl). Iodine content in artificial infant milk preparations was of a similar range. These results indicate that iodine supply during the neonatal period in the Federal Republic of Germany is very low; they support the demand for general iodine-salt prophylaxis.

摘要

对来自德意志联邦共和国九个不同城镇的461名新生儿在出生后第五天测量了尿碘排泄量。从北到南,尿碘水平呈逐渐下降趋势,汉堡的水平最高(2.9微克/分升),弗赖堡的水平最低(1.2微克/分升)。所有这些水平均低于其他在食盐中加碘的国家的新生儿水平:斯德哥尔摩(61名新生儿)为9.6微克/分升,苏黎世(63名)为4.75微克/分升。对哥廷根产后第五天的母亲进行的碘分析表明,患有甲状腺肿的母亲(51例)尿碘排泄量显著低于无甲状腺肿的对照组(38例):分别为17.6微克/克肌酐和30.0微克/克肌酐,并且甲状腺肿组母乳中的碘含量显著低于对照组(分别为1.75微克/分升和2.5微克/分升)。人工婴儿奶粉制剂中的碘含量处于类似范围。这些结果表明,德意志联邦共和国新生儿期的碘供应非常低;它们支持了普遍进行碘盐预防的需求。

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