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[血浆蛋白和β-脂蛋白在动脉粥样硬化冠状动脉壁中的定位]

[Localization of plasma proteins and beta-lipoproteins in the walls of arteriosclerotic coronary arteries].

作者信息

Iakovleva N I

出版信息

Kardiologiia. 1977 Jan;17(1):114-9.

PMID:67237
Abstract

Immunofluorescent analysis was used to study the topography of plasma proteins and beta-lipoproteins in the wall of human coronary arteries in cases of atherosclerosis. The dynamics of protein fractions deposits is not uniform in the process of the formation of the disease. Along with the progress of atherosclerosis, the infiltration of proteins, lipoproteins and lipids is increasing. A regular combination of beta-lipoproteins and gamma-globulin localizations was established. The role of the examined components in the wall of the coronary arteries and their participation in the formation of atherosclerotic plaques is discussed.

摘要

免疫荧光分析用于研究动脉粥样硬化病例中人类冠状动脉壁内血浆蛋白和β-脂蛋白的分布情况。在疾病形成过程中,蛋白质组分沉积的动态变化并不一致。随着动脉粥样硬化的进展,蛋白质、脂蛋白和脂质的浸润不断增加。已确定β-脂蛋白和γ-球蛋白定位之间存在规律组合。文中讨论了所检测成分在冠状动脉壁中的作用及其在动脉粥样硬化斑块形成中的参与情况。

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