伴刀豆球蛋白A、触珠蛋白和胰蛋白酶之间的结构相似性。
Structural similarities among concanavalin A, haptoglobin, and trypsin.
作者信息
Dobryszycka W, Przysiecki B
出版信息
FEBS Lett. 1984 Jun 4;171(1):85-8. doi: 10.1016/0014-5793(84)80464-0.
PMID:6723978
Abstract
Comparison of the primary structure of concanavalin A with those of trypsin and beta (heavy) chain of haptoglobin revealed a significant degree of chemical similarity. The amino acid sequence of concanavalin A was found to be 53.6% related to trypsin and haptoglobin. Certain analogy in the tertiary structure was shown by the use of thionine binding to the specific active site, characteristic for serine proteases.
摘要
伴刀豆球蛋白A的一级结构与胰蛋白酶和触珠蛋白的β（重）链的一级结构相比较，显示出显著程度的化学相似性。发现伴刀豆球蛋白A的氨基酸序列与胰蛋白酶和触珠蛋白有53.6%的相关性。通过使用硫堇结合到丝氨酸蛋白酶特有的特定活性位点，显示出三级结构上的某些相似性。
相似文献
1
Structural similarities among concanavalin A, haptoglobin, and trypsin.伴刀豆球蛋白A、触珠蛋白和胰蛋白酶之间的结构相似性。
FEBS Lett. 1984 Jun 4;171(1):85-8. doi: 10.1016/0014-5793(84)80464-0.
2
Covalent structure of human haptoglobin: a serine protease homolog.人触珠蛋白的共价结构：一种丝氨酸蛋白酶同源物。
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3388-92. doi: 10.1073/pnas.77.6.3388.
3
Model for haptoglobin heavy chain based upon structural homology.基于结构同源性的触珠蛋白重链模型。
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3393-7. doi: 10.1073/pnas.77.6.3393.
4
Di-, tri-, and tetrapeptide sequences in haptoglobin. Contribution to understanding of haptoglobin structure.触珠蛋白中的二肽、三肽和四肽序列。对理解触珠蛋白结构的贡献。
Acta Biochim Pol. 1982;29(3-4):299-309.
5
Studies on haptoglobin binding to concanavalin A.结合伴刀豆球蛋白A的触珠蛋白研究。
Biochim Biophys Acta. 1984 Oct 9;790(1):8-14. doi: 10.1016/0167-4838(84)90325-x.
6
Evidence of homology between the beta-chain of human haptoglobin and the chymotrypsin family of serine proteases.人触珠蛋白β链与丝氨酸蛋白酶胰凝乳蛋白酶家族之间的同源性证据。
Biochem Genet. 1974 Apr;11(4):279-93. doi: 10.1007/BF00485995.
7
Hemoglobin binding site and its relationship to the serine protease-like active site of haptoglobin.血红蛋白结合位点及其与触珠蛋白丝氨酸蛋白酶样活性位点的关系。
J Biol Chem. 1982 Sep 10;257(17):10063-8.
8
[trypsin inhibition by sheep haptoglobin].
Biokhimiia. 1988 Jul;53(7):1082-5.
9
Products of trypsin digestion of haptoglobin beta (heavy) chain.
Int J Biochem. 1985;17(8):917-23. doi: 10.1016/0020-711x(85)90176-4.
10
Characterization of the cyanogen bromide fragments of the beta chain of human haptoglobin.人触珠蛋白β链溴化氰片段的特性分析
Biochemistry. 1976 Nov 30;15(24):5326-36. doi: 10.1021/bi00669a020.
Zotero 插件