斯普拉格-道利大鼠的卵巢肿瘤形成

Department of Pathology, Huntingdon Research Centre, Cambridgeshire, England.

Environ Health Perspect. 1987 Aug;73:77-90. doi: 10.1289/ehp.877377.

Macroscopic and microscopic characteristics of 210 spontaneous ovarian tumors from 7748 Sprague-Dawley rats are described. The tumors were classified as tubular adenoma, anaplastic adenocarcinoma, papillary cystadenoma, papillary cystadenocarcinoma, mesothelioma, sertoliform tubular adenoma, Sertoli's cell tumor, granulosa cell tumor, thecal cell tumor, polycystic sex cord/stromal tumor, and lipoid cell tumor. The histogenesis of the tumor types is discussed.

描述了7748只斯普拉格-道利大鼠中210个自发性卵巢肿瘤的宏观和微观特征。这些肿瘤被分类为管状腺瘤、间变性腺癌、乳头状囊腺瘤、乳头状囊腺癌、间皮瘤、睾丸样管状腺瘤、支持细胞瘤、颗粒细胞瘤、卵泡膜细胞瘤、多囊性性索/间质瘤和类脂质细胞瘤。讨论了肿瘤类型的组织发生。