Sutton J R
Med Sci Sports. 1978 Spring;10(1):1-6.
Hormonal and metabolic responses to submaximal were studied in eight normal subjects. Four subjects had high maximal oxygen uptakes (455 +/- 0.49/min) and were classified as "fit" and four had low maximal oxygen uptakes (2.13 +/- 0.32 1/min) and were classified as "unfit". All subjects exercised for 20 minutes at 750 kpm/min on a cycle ergometer, which represented 35% and 85% of the maximal oxygen uptake for the fit and the unfit subjects respectively. The unfit subjects had a higher heart rate and CO2 output at the same oxygen uptake when compared with the fit group. There was a high blood lactate in the unfit subjects and also a greater rise in blood glucose, plasma cortisol and serum growth hormone during exercise in these subjects. Free fatty acids increased in the fit subjects, but not in the unfit and serum insulin was depressed in both groups. Thus, the cardiorespiratory fitness is an important determinant of the hormonal and metabolic response to submaximal exercise, which differed considerably when fit and unfit subjects exercised at identical absolute levels of power output. These differences have implications for the control of energy substrates used during exercise.
对八名正常受试者进行了次最大运动时的激素和代谢反应研究。四名受试者最大摄氧量较高（455±0.49升/分钟），被归类为“健康”，另外四名最大摄氧量较低（2.13±0.32升/分钟），被归类为“不健康”。所有受试者在自行车测力计上以750千帕米/分钟的速度运动20分钟，这一强度分别相当于健康受试者和不健康受试者最大摄氧量的35%和85%。与健康组相比，不健康受试者在相同摄氧量时心率和二氧化碳排出量更高。不健康受试者血液乳酸含量较高，运动期间血糖、血浆皮质醇和血清生长激素的升高幅度也更大。健康受试者游离脂肪酸增加，不健康受试者则未增加，两组血清胰岛素均降低。因此，心肺功能是次最大运动时激素和代谢反应的重要决定因素，当健康和不健康受试者以相同绝对功率输出水平运动时，两者的反应差异很大。这些差异对运动期间能量底物的控制具有重要意义。
