Kohn S, Haim S, Gilhar A, Friedman-Birnbaum R, Nir I
J Clin Pathol. 1984 Jun;37(6):616-9. doi: 10.1136/jcp.37.6.616.
Langerhans' cells were studied in the epidermis of two patients with active Behçet's disease and compared with those in two normal controls. Ultrastructural morphology and the percentage of Langerhans' cells found were similar in patients' (1.88%) and the control epidermis (1.79%). The density of Langerhans' cells in adjacent sites of the same epidermis was not homogeneous, being in the range of 0.8-2.8% in Behçet's disease and 0.6-4% in the controls. In the controls, Langerhans' cells were distributed unevenly. Some were located near the basal layer of the epidermis while the rest were in the mid and upper layers. In Behçet's disease most Langerhans' cells were in the mid-epidermis, but some were immediately beneath the stratum granulosum. In the Behçet's disease epidermis the area occupied by Langerhans' cells was increased by about 25% and the number of granules found increased by about 44%. It is suggested that in Behçet's disease the Langerhans' cells are in a more active state.
对两名患有活动期白塞病患者的表皮中的朗格汉斯细胞进行了研究，并与两名正常对照者的进行了比较。患者（1.88%）和对照表皮（1.79%）中朗格汉斯细胞的超微结构形态及所占百分比相似。同一表皮相邻部位朗格汉斯细胞的密度并不均匀，白塞病患者中为0.8 - 2.8%，对照者中为0.6 - 4%。在对照者中，朗格汉斯细胞分布不均。一些位于表皮基底层附近，其余的位于中层和上层。在白塞病中，大多数朗格汉斯细胞位于表皮中层，但有些紧邻颗粒层下方。在白塞病表皮中，朗格汉斯细胞所占面积增加了约25%，发现的颗粒数量增加了约44%。提示在白塞病中朗格汉斯细胞处于更活跃的状态。
