Palmieri T J
J Hand Surg Am. 1984 May;9(3):332-8. doi: 10.1016/s0363-5023(84)80218-x.
Eighteen consecutive cases with the histologic diagnosis of chondrosarcoma of the hand were reviewed and followed up from 1 to 10 years. The primary tumor originated without a preexisting lesion in 78%. Secondary tumors arose in patients who had multiple enchondromas but not in patients with a solitary enchondroma. The onset is usually in the 60- to 80-year age group with the tumor almost always occurring in the epiphyseal area of the proximal phalanx (56%) or the metacarpals (39%). Roentgenographic features included indiscrete lytic areas of bone destruction (83%). The diagnostic finding of intraosseous or extraosseous scattered, punctate, calcific densities of dystrophic calcification occurred in 66%. Ray resection of the tumor is the treatment of choice. Local recurrences occurred in 11% and distant metastases were not seen.
回顾性分析了18例经组织学诊断为手部软骨肉瘤的连续病例,并进行了1至10年的随访。78%的原发性肿瘤起源于无先前病变的部位。继发性肿瘤发生在患有多发性内生软骨瘤的患者中,而孤立性内生软骨瘤患者未发生。发病年龄通常在60至80岁,肿瘤几乎总是发生在近端指骨(56%)或掌骨(39%)的骨骺区域。X线特征包括不连续的骨质破坏溶解区(83%)。66%的病例在骨内或骨外出现散在、点状、营养不良性钙化的密度影,这是诊断的依据。肿瘤的射线切除是首选治疗方法。局部复发率为11%,未见远处转移。