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无名指去分化软骨肉瘤:一例特殊手术治疗病例报告及文献综述

Dedifferentiated chondrosarcoma of the ring finger: a case report of an exceptional surgical treatment and review of literature.

作者信息

Mani Olimpia, Andreani Lorenzo, D'Arienzo Antonio, Colangeli Simone, Capanna Rodolfo

机构信息

II Department of Orthopedic and Trauma Surgery, University of Pisa, Italy, University of Pisa.

II Department of Orthopedic and Trauma Surgery, University of Pisa, Italy, AOUP.

出版信息

Orthop Rev (Pavia). 2022 Apr 25;14(3):33581. doi: 10.52965/001c.33581. eCollection 2022.

Abstract

The DDCS is a rare, highly malignant tumor characterized by two distinct histopathologic components. The diagnosis is insidious, and the prognosis is poor. The therapy is primarily surgical. It is possible to associate chemotherapy if the nonchondrogenic component is a responder. Unfortunately, very few cases of DDCS of the hand are described in the literature. Therefore, few scientific comparisons are possible regarding diagnosis and therapy. For this reason, we decided to present a sporadic case of DDCS of the fourth finger of the left hand, presented with a seven months history of pain and swelling, which appeared after the treatment of recurrent enchondroma and was treated with amputation and complex reconstruction. To our knowledge, no similar cases have been previously reported in the literature.

摘要

双相性软骨肉瘤(DDCS)是一种罕见的高度恶性肿瘤,具有两种不同的组织病理学成分。其诊断隐匿,预后较差。治疗主要以手术为主。如果非软骨生成成分有反应,可联合化疗。不幸的是,文献中描述的手部DDCS病例极少。因此,关于诊断和治疗几乎没有科学的比较。出于这个原因,我们决定展示一例左手无名指的散发性DDCS病例,该病例有7个月的疼痛和肿胀病史,在复发性内生软骨瘤治疗后出现,接受了截肢和复杂重建治疗。据我们所知,此前文献中尚未报道过类似病例。

相似文献

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Dedifferentiated chondrosarcoma of the thumb: a case report.拇指去分化软骨肉瘤:一例报告
Arch Orthop Trauma Surg. 2009 Feb;129(2):161-6. doi: 10.1007/s00402-007-0538-x. Epub 2007 Dec 6.

本文引用的文献

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Acral Dedifferentiated Chondrosarcoma of a Toe Phalanx: A Case Report.趾骨远端去分化软骨肉瘤:一例报告
JBJS Case Connect. 2014 Feb 12;4(1 Suppl. 4):e16. doi: 10.2106/JBJS.CC.M.00214.
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Enchondroma of the Hand: Evaluation and Management.手部内生软骨瘤:评估与处理
J Am Acad Orthop Surg. 2016 Sep;24(9):625-33. doi: 10.5435/JAAOS-D-15-00452.
7
Dedifferentiated chondrosarcoma of the thumb: a case report.拇指去分化软骨肉瘤:一例报告
Arch Orthop Trauma Surg. 2009 Feb;129(2):161-6. doi: 10.1007/s00402-007-0538-x. Epub 2007 Dec 6.
10
Experience in the treatment of dedifferentiated chondrosarcoma.去分化软骨肉瘤的治疗经验。
J Bone Joint Surg Br. 2000 Jan;82(1):55-61. doi: 10.1302/0301-620x.82b1.9020.

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