Lemish I, Bennett F, Martin C, Warwick A, Quinlan M
J Nucl Med. 1984 Jan;25(1):49-55.
This paper describes a practical procedure to establish a sensitive radioimmunoassay for the measurement of human thyroglobulin (HTg) in serum. The assay enables a clear distinction to be made between levels of HTg indicating the presence or absence of functioning thyroid tissue. It compares the use of HTg serum levels with the conventional I-131 scintigram as a marker for recurrent thyroid cancer. In addition, a simple and sensitive radioimmunologic assay is described for the determination of serum antithyroglobulin autoantibodies, the presence of which may give falsely elevated HTg levels.
本文描述了一种建立灵敏放射免疫分析法以测定血清中人类甲状腺球蛋白（HTg）的实用程序。该分析方法能够明确区分表明功能性甲状腺组织存在与否的HTg水平。它将HTg血清水平的应用与传统的I-131闪烁扫描图作为复发性甲状腺癌标志物进行了比较。此外，还描述了一种用于测定血清抗甲状腺球蛋白自身抗体的简单灵敏放射免疫分析方法，该自身抗体的存在可能会使HTg水平出现假性升高。
