Guilleminault C, Coons S
J Pediatr. 1984 Jun;104(6):932-5. doi: 10.1016/s0022-3476(84)80502-8.
One full-term and nine premature infants who had been or were about to be discharged from the hospital were studied to identify any breathing problems. While awake and when sucking and swallowing, the infants had central apnea accompanied by significant bradycardia and significant drops in transcutaneous oxygen values. These events occurred whether infants were breast-fed or ingested human milk, formula, or water by bottle, and were not associated with falls in esophageal pH. While awake, after occlusion of both nostrils, the infants responded with mouth breathing. Sleep-related apneic episodes were also found but were less significant. The long apneic events were related to poorly coordinated sucking and breathing while awake.
对一名足月儿和九名已出院或即将出院的早产儿进行了研究，以确定是否存在任何呼吸问题。在清醒状态下以及吸吮和吞咽时，这些婴儿出现中枢性呼吸暂停，并伴有显著的心动过缓和经皮氧值大幅下降。无论婴儿是母乳喂养还是通过奶瓶摄入母乳、配方奶或水，这些情况都会发生，并且与食管pH值下降无关。在清醒状态下，双侧鼻孔堵塞后，婴儿会用口呼吸。还发现了与睡眠相关的呼吸暂停发作，但不太明显。长时间的呼吸暂停事件与清醒时吸吮和呼吸协调不佳有关。
