Alarcón-Segovia D, Abud-Mendoza C, Reyes-Gutiérrez E, Iglesias-Gamarra A, Díaz-Jouanen E
J Rheumatol. 1984 Apr;11(2):208-10.
Urinary bladder histologic changes were found in 16 of 35 necropsies from systemic lupus erythematosus (SLE) patients in whom adequate material was available for study. These included interstitial cystitis (n = 11), hemorrhage (n = 9), congestion (n = 7), vasculitis (n = 5), and perivenular infiltrate (n = 4). Abnormalities were found in only 5 of 30 control necropsies from patients with other diseases and in 4 of them these were hemorrhagic and chiefly due to indwelling catheters. SLE patients with histologic bladder changes were found to have pulmonary hemorrhage more frequently than those without. This suggests a common pathogenetic mechanism between interstitial cystitis and pulmonary hemorrhage in SLE.
在35例系统性红斑狼疮（SLE）患者的尸检中，有16例获得了足够用于研究的材料，并发现了膀胱组织学变化。这些变化包括间质性膀胱炎（11例）、出血（9例）、充血（7例）、血管炎（5例）和血管周围浸润（4例）。在30例其他疾病患者的对照尸检中，只有5例发现异常，其中4例为出血，主要是由于留置导管所致。发现有膀胱组织学变化的SLE患者比没有这种变化的患者更常发生肺出血。这表明SLE中间质性膀胱炎和肺出血之间存在共同的发病机制。
