Fröhli P, Streuli R, Rhyner K
Klin Wochenschr. 1984 May 2;62(9):412-6. doi: 10.1007/BF01742298.
In twenty patients suffering from myeloproliferative syndromes (nine with polycythaemia vera, 11 with primary thrombocythaemia) platelet aggregation was tested following incubation of blood samples at 4 degrees C, room temperature, 30 degrees C and 37 degrees C. A spontaneous platelet aggregation following incubation at room temperature took place in 65% of patients with primary thrombocythaemia. At the two higher temperatures, positive results were seen in 72% and 92% of cases, respectively. Seven of nine patients (78%) showed a pathological spontaneous platelet aggregation at room temperature. Pathological spontaneous platelet aggregation at 30 degrees C occurred in eight of nine (89%) cases. The spontaneous platelet aggregation test is a simple method to diagnose primary thrombocythaemia and asymptomatic polycythaemia vera, the sensitivity of which increases considerably following incubation of blood samples at two and three different temperatures.
对20例骨髓增殖性综合征患者（9例真性红细胞增多症，11例原发性血小板增多症），在4℃、室温、30℃和37℃下孵育血样后检测血小板聚集情况。原发性血小板增多症患者中，65%在室温孵育后出现自发性血小板聚集。在两个较高温度下，分别有72%和92%的病例出现阳性结果。9例患者中有7例（78%）在室温下出现病理性自发性血小板聚集。9例中有8例（89%）在30℃时出现病理性自发性血小板聚集。自发性血小板聚集试验是诊断原发性血小板增多症和无症状真性红细胞增多症的一种简单方法，在血样于两个及三个不同温度下孵育后，其敏感性会显著提高。
