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[慢性酒精中毒患者的系统性动脉高血压。戒酒综合征的作用]

[Systemic arterial hypertension in chronic alcoholics. Role of the abstinence syndrome].

作者信息

Gheno G, Attard B, Mazzei G

出版信息

Minerva Med. 1984 May 7;75(19):1123-8.

PMID:6728261
Abstract

A significantly positive association (p less than 0.001) has been shown between so called "minor" ethanol withdrawal-syndrome and raised systolic and diastolic blood pressure values in 328 hospitalized chronic alcoholics. In a subgroup of patients with clinical and histological findings of alcoholic hepatic cirrhosis, this association was absent (p greater than 0.5). In chronic alcoholics with several hospital admissions, a nearly constant relationship of "minor" ethanol withdrawal-syndrome to systolic and diastolic hypertension has been shown. Mild or early abstinence states in alcoholics - which may pass off undetected or misinterpreted in outpatient clinic examination - are possibly responsible for the positive association between hypertension and alcoholism reported by others in several epidemiologic studies. Therefore, high blood pressure values in a chronic alcoholic patient - even if detected on several occasions - need special clinical considerations and we think they do not mean alcohol-induced hypertension. From another point of view, high blood pressure values may give a hint for detection of hidden alcoholism.

摘要

在328名住院慢性酒精中毒患者中,所谓的“轻度”乙醇戒断综合征与收缩压和舒张压升高之间存在显著正相关(p小于0.001)。在有酒精性肝硬化临床和组织学表现的患者亚组中,这种相关性不存在(p大于0.5)。在多次入院的慢性酒精中毒患者中,“轻度”乙醇戒断综合征与收缩期和舒张期高血压之间存在近乎恒定的关系。酒精中毒者的轻度或早期戒酒状态——在门诊检查中可能未被发现或被误解——可能是其他几项流行病学研究中报道的高血压与酒精中毒之间正相关的原因。因此,慢性酒精中毒患者的高血压值——即使多次检测到——也需要特殊的临床考虑,我们认为这并不意味着酒精性高血压。从另一个角度来看,高血压值可能为发现隐匿性酒精中毒提供线索。

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