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[慢性酒精中毒与动脉高血压。对该现象理解及实际影响的贡献]

[Chronic alcoholism and arterial hypertension. Contribution to the comprehension of the phenomenon and practical implications].

作者信息

Isa L, Baldini G, Moriglioni M, Zaina A, Bocchia M

机构信息

Divisione di Medicina, Ospedale, Gorgonzola.

出版信息

Recenti Prog Med. 1992 Sep;83(9):489-91.

PMID:1439115
Abstract

Alcohol abuse is a frequent contributor to elevated blood pressure. 710 chronic alcoholics, aged 26-60 years, admitted for detoxification were studied. We compared hypertension prevalence in alcoholics with that in a similar group of non-alcoholics matched for age, sex, and miscellaneous diseases. The prevalence of hypertension was higher in heavy drinkers (11.4%) than in non drinker subjects (3.4%). Abstinence from alcohol during hospitalization was followed by normalization of hypertensive status in a high percentage of patients (70%). The majority of hypertensive alcoholics (75%) developed target organ damage ranging from retinopathy to hypertensive cardiomyopathy and renal lesion. In a 4.6 +/- 2.8 years follow-up study of 42 hypertensive alcoholic subjects, we observed that hypertension was 26% in those who abstained alcohol ingestion versus 84% in those who remained actively alcoholics. Four patients died of liver failure and two of stroke.

摘要

酒精滥用是血压升高的常见原因。对710名年龄在26至60岁之间因戒酒入院的慢性酒精中毒者进行了研究。我们将酗酒者的高血压患病率与一组年龄、性别和杂病相匹配的非酗酒者进行了比较。重度饮酒者的高血压患病率(11.4%)高于非饮酒者(3.4%)。住院期间戒酒的患者中,很大一部分(70%)的高血压状态得以恢复正常。大多数高血压酗酒者(75%)出现了从视网膜病变到高血压性心肌病和肾脏病变等靶器官损害。在对42名高血压酗酒者进行的4.6±2.8年的随访研究中,我们观察到,戒酒者的高血压患病率为26%,而仍积极酗酒者的患病率为84%。4名患者死于肝功能衰竭,2名死于中风。

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