Takeuchi Y, Hopkins D A
Neurosci Lett. 1984 Apr 20;46(1):53-8. doi: 10.1016/0304-3940(84)90198-8.
Hypothalamic connections with the parabrachial nuclei in the cat were studied at light and electron microscopic levels following wheat germ agglutinin-horseradish peroxidase injections into the parabrachial nuclei and electrolytic lesions in the hypothalamus. The greatest concentration of retrogradely labeled neurons occurred in the paraventricular nucleus. Labeled neurons were also seen within the preoptic, anterior, lateral, dorsomedial and ventromedial hypothalamic nuclei. Hypothalamic lesions resulted in the degeneration of terminals forming axosomatic and axodendritic synapses in the parabrachial nuclei, particularly its lateral division. These findings support the idea that hypothalamic connections to specific regions of the parabrachial nuclei may underlie the topographical functional organization demonstrated for these brainstem nuclei.
在将小麦胚芽凝集素-辣根过氧化物酶注入猫的臂旁核并在下丘脑进行电解损伤后，在光学和电子显微镜水平上研究了下丘脑与臂旁核之间的联系。逆行标记神经元的最大浓度出现在室旁核中。在视前区、下丘脑前核、外侧核、背内侧核和腹内侧核内也可见到标记神经元。下丘脑损伤导致臂旁核中形成轴体和轴树突触的终末发生变性，尤其是其外侧部。这些发现支持这样一种观点，即下丘脑与臂旁核特定区域的联系可能是这些脑干核所表现出的拓扑功能组织的基础。
