Grossman S P
Neurosci Biobehav Rev. 1984 Spring;8(1):95-104. doi: 10.1016/0149-7634(84)90023-x.
The classic " hypothalamocentric " theory of thirst has increasingly been challenged because the effects of hypothalamic lesions are not as behaviorally or anatomically specific as earlier research indicated. Instead, the attention of investigators in the field has increasingly been drawn to the lateral preoptic region and the tissues surrounding the anterior third ventricle. The present paper reviews these developments and proposes that still another diencephalic structure, the subthalamic region known as the zona incerta, may play a major role in the regulation of thirst and water intake.
经典的关于口渴的“下丘脑中心”理论越来越受到挑战，因为下丘脑损伤的影响在行为或解剖学上并不像早期研究所表明的那样具有特异性。相反，该领域研究人员的注意力越来越多地被吸引到视前外侧区和第三脑室前部周围的组织。本文回顾了这些进展，并提出另一个间脑结构，即被称为未定带的丘脑底区域，可能在口渴和水摄入的调节中起主要作用。
