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大脑和阴囊热刺激期间大鼠中枢温敏神经元的激活及尾部血管舒缩反应

Activation of central warm-sensitive neurons and the tail vasomotor response in rats during brain and scrotal thermal stimulation.

作者信息

Ishikawa Y, Nakayama T, Kanosue K, Matsumura K

出版信息

Pflugers Arch. 1984 Mar;400(3):222-7. doi: 10.1007/BF00581551.

DOI:10.1007/BF00581551
PMID:6728642
Abstract

The effects of preoptic and hypothalamic thermal stimulation on tail skin temperature were observed at different scrotal temperatures. The threshold hypothalamic temperature for tail vasodilation at a scrotal temperature of 40 degrees C was significantly lower than that at a scrotal temperature of either 25 degrees C or 33 degrees C. The effects of scrotal thermal stimulation on tail skin vasodilated by higher hypothalamic temperatures were observed. Cooling the scrotum from 42 to 30 degrees C invariably caused a rapid fall in tail temperature, whereas scrotal cooling from 30 to 25 degrees C did not cause any significant change. Cooling of either the left or right half of the scrotum caused a similar fall in tail temperature. The temperature characteristics of the preoptic hypothalamic thermo-sensitive neurons were determined at scrotal temperatures of 32, 36 and 26 degrees C. The firing rate of warm-sensitive neurons at a given hypothalamic temperature was highest at a scrotal temperature of 36 degrees C, while that of cold-sensitive neurons was lowest at that temperature. The scrotal temperature range over which the number of neurons activated by scrotal warming increased rapidly was between 36 and 39 degrees C when hypothalamic temperature was held at 36-37 degrees C.

摘要

在不同阴囊温度下,观察视前区和下丘脑热刺激对尾部皮肤温度的影响。在阴囊温度为40℃时,尾部血管舒张的下丘脑温度阈值显著低于阴囊温度为25℃或33℃时的阈值。观察了阴囊热刺激对下丘脑较高温度引起的尾部皮肤血管舒张的影响。将阴囊温度从42℃降至30℃总是会导致尾部温度迅速下降,而阴囊温度从30℃降至25℃则不会引起任何显著变化。阴囊左半侧或右半侧的冷却都会导致尾部温度出现类似下降。在阴囊温度为32℃、36℃和26℃时,测定视前区下丘脑热敏神经元的温度特征。在给定的下丘脑温度下,热敏神经元的放电频率在阴囊温度为36℃时最高,而冷敏神经元的放电频率在该温度下最低。当下丘脑温度保持在36 - 37℃时,阴囊升温激活神经元数量迅速增加的阴囊温度范围在36℃至39℃之间。

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Activation of central warm-sensitive neurons and the tail vasomotor response in rats during brain and scrotal thermal stimulation.大脑和阴囊热刺激期间大鼠中枢温敏神经元的激活及尾部血管舒缩反应
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