用于筛选具有肿瘤定位特性的潜在放射性药物的发育中胎盘：一种简单的体内预筛选模型
The developing placenta in selecting potential radiopharmaceuticals for tumour-localizing properties: a simple in vivo pre-screening model.
作者信息
Hoekstra A, Vos C M, Herscheid J D
出版信息
Nuklearmedizin. 1984 Feb;23(1):19-21.
PMID:6728689
Abstract
The tissue distribution of various radiopharmaceuticals was investigated in rhabdomyosarcoma-bearing and in pregnant rats during the period of rapid foetal and placental growth (days 17-19 of pregnancy). The preliminary results indicate that with the radiopharmaceuticals tested the uptake in placental tissue followed closely the data obtained with tumour tissue in rhabdomyosarcoma-bearing rats.
摘要
在携带横纹肌肉瘤的大鼠以及处于胎儿和胎盘快速生长阶段（妊娠第17 - 19天）的怀孕大鼠中，研究了各种放射性药物的组织分布。初步结果表明，在所测试的放射性药物中，胎盘组织的摄取情况与携带横纹肌肉瘤大鼠的肿瘤组织摄取数据密切相关。
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