甲状腺功能减退症中硝西泮代谢受损。
Impaired nitrazepam metabolism in hypothyroidism.
作者信息
Kenny R A, Kafetz K, Cox M, Timmers J, Impallomeni M
出版信息
Postgrad Med J. 1984 Apr;60(702):296-7. doi: 10.1136/pgmj.60.702.296.
Abstract
Delayed metabolism of a number of drugs has been described in hypothyroid patients. We report an elderly hypothyroid female who had prolonged delay in the metabolism of a commonly-used sedative, nitrazepam, and discuss the importance of delayed drug metabolism in hypothyroidism.
摘要
甲状腺功能减退患者中多种药物代谢延迟已有相关描述。我们报告了一位老年甲状腺功能减退女性患者，她对常用镇静剂硝西泮的代谢存在长期延迟，并讨论了甲状腺功能减退中药物代谢延迟的重要性。
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本文引用的文献
1
Clinical pharmacokinetics of nitrazepam.硝西泮的临床药代动力学
Clin Pharmacokinet. 1981 Sep-Oct;6(5):346-66. doi: 10.2165/00003088-198106050-00002.
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Influence of thyroid dysfunction on drug pharmacokinetics.甲状腺功能障碍对药物药代动力学的影响。
Clin Pharmacokinet. 1981 Jul-Aug;6(4):275-97. doi: 10.2165/00003088-198106040-00003.
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Screening for hypothyroidism in elderly inpatients.老年住院患者甲状腺功能减退症的筛查
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