Bahemuka M, Hodkinson H M
Br Med J. 1975 Jun 14;2(5971):601-3. doi: 10.1136/bmj.2.5971.601.
Routine biochemical screening for hypothyroidism in 2000 geriatric inpatients proved valuable and practicable and yielded 46 cases (2.3%). A non-specific clinical picture was particularly common, with less than a third of the cases showing "typical" signs and symptoms. Psychiatric manifestations, especially depression, were important and frequent and responded well to thyroxine. There was a preponderance of female cases of hypothyroidism and a strong association with other autoimmune diseases, notably pernicious anaemia and rheumatoid arthritis.
对2000名老年住院患者进行甲状腺功能减退症的常规生化筛查,结果证明该筛查既实用又有价值,共查出46例(2.3%)。非特异性临床表现尤为常见,不到三分之一的病例有“典型”体征和症状。精神症状,尤其是抑郁症,既常见又重要,对甲状腺素治疗反应良好。甲状腺功能减退症女性患者居多,且与其他自身免疫性疾病密切相关,尤其是恶性贫血和类风湿关节炎。