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细胞对重力的敏感性。

Cell sensitivity to gravity.

作者信息

Cogoli A, Tschopp A, Fuchs-Bislin P

出版信息

Science. 1984 Jul 13;225(4658):228-30. doi: 10.1126/science.6729481.

DOI:10.1126/science.6729481
PMID:6729481
Abstract

Cultures of human lymphocytes exposed in microgravity to the mitogen concanavalin A showed less than 3 percent of the activation of ground controls. This result supports the hypothesis, based on simulations at low g and experiments at high g, that microgravity depresses whereas high gravity enhances cell proliferation rates. The effects of gravity are particularly strong in cells undergoing differentiation.

摘要

在微重力环境下暴露于促细胞分裂剂伴刀豆球蛋白A的人类淋巴细胞培养物,其激活程度不到地面对照的3%。这一结果支持了基于低重力模拟和高重力实验得出的假设,即微重力会抑制而高重力会提高细胞增殖速率。重力对正在分化的细胞影响尤为强烈。

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Science. 1984 Jul 13;225(4658):228-30. doi: 10.1126/science.6729481.
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