Celli P, Ferrante L, Palma L, Cavedon G
Surg Neurol. 1984 Jul;22(1):43-9. doi: 10.1016/0090-3019(84)90227-1.
A study of 19 children with cerebral arteriovenous malformation (AVM) is reported; these children represent 12% of 161 patients with this disease at the Rome University Institute of Neurosurgery. The published data on intracranial arteriovenous malformations in children and in adults are reviewed and the clinical features and results of treatment in the two age groups compared. The results of surgical removal seem to be better in children while the follow-up mortality with conservative treatment is higher. The last point receives indirect confirmation from a study of the risk of bleeding in which the patients of our series were compared by age at clinical onset, viz. those under 15 years of age and those over 15 years. After an average follow-up of slightly over 10 years, the risk of bleeding is higher with onset before the age 15 years and significantly higher if the onset is nonhemorrhagic.
本文报告了一项对19例脑动静脉畸形（AVM）患儿的研究；这些患儿占罗马大学神经外科研究所161例该疾病患者的12%。本文回顾了已发表的关于儿童和成人颅内动静脉畸形的数据，并比较了两个年龄组的临床特征和治疗结果。手术切除的结果在儿童中似乎更好，而保守治疗的随访死亡率更高。通过一项关于出血风险的研究间接证实了最后一点，在该研究中，对我们系列中的患者按临床发病年龄进行了比较，即15岁以下和15岁以上的患者。经过略超过10年的平均随访，15岁之前发病的出血风险更高，如果发病是非出血性的，则出血风险显著更高。
