Kistler J P, Buonanno F S, DeWitt L D, Davis K R, Brady T J, Fisher C M
Stroke. 1984 May-Jun;15(3):417-26. doi: 10.1161/01.str.15.3.417.
We used three-dimensional proton NMR images to study ischemic infarction in the territory of the vertebral-basilar posterior cerebral circulation. The study includes sixteen cases, eight of which are presented in detail. In seven cases, the infarctions were secondary to demonstrable large artery occlusive disease -- vertebral, basilar, or posterior cerebral. In nine cases, the infarctions were secondary to what was presumably small vessel disease. In fifteen of the sixteen cases, NMR imaging could locate the infarct, inversion recovery and spin-echo pulse sequences being more sensitive than the saturation recovery pulse sequence. This efficiency rests on the high sensitivity of ischemic infarction to changes in T1 and T2 relaxation time, highlighted in the inversion recovery and spin-echo images, respectively. The additional advantages of the three-dimensional approach, and the lack of bone artifact, make NMR imaging superior to CT scanning in identifying areas of infarction in the territory of posterior cerebral circulation.
我们使用三维质子核磁共振成像来研究椎基底动脉后循环区域的缺血性梗死。该研究包括16例病例，其中8例将详细呈现。在7例病例中，梗死继发于可证实的大动脉闭塞性疾病——椎动脉、基底动脉或大脑后动脉。在9例病例中，梗死继发于推测的小血管疾病。在16例病例中的15例中，核磁共振成像能够定位梗死灶，反转恢复序列和自旋回波脉冲序列比饱和恢复脉冲序列更敏感。这种有效性基于缺血性梗死对T1和T2弛豫时间变化的高敏感性，分别在反转恢复图像和自旋回波图像中得到凸显。三维成像方法的额外优势以及无骨质伪影，使得核磁共振成像在识别大脑后循环区域的梗死灶方面优于CT扫描。
