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The kinetic constants for the extraneuronal uptake and metabolism of 3H-(-)-noradrenaline in the perfused rat heart.

作者信息

Fiebig E R, Trendelenburg U

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1978 May;303(1):37-45. doi: 10.1007/BF00496183.

DOI:10.1007/BF00496183
PMID:673015
Abstract
摘要

相似文献

1
The kinetic constants for the extraneuronal uptake and metabolism of 3H-(-)-noradrenaline in the perfused rat heart.灌注大鼠心脏中3H-（-）-去甲肾上腺素的神经元外摄取和代谢的动力学常数。
Naunyn Schmiedebergs Arch Pharmacol. 1978 May;303(1):37-45. doi: 10.1007/BF00496183.
2
Lack of differences between the neuronal and extraneuronal handling of 3H-7- and 3H-ring-2,5,6-(-)noradrenaline.3H - 7 - 去甲肾上腺素和3H - 环 - 2,5,6 -（-）去甲肾上腺素在神经元和非神经元处理方面缺乏差异。
Naunyn Schmiedebergs Arch Pharmacol. 1988 Aug;338(2):180-4. doi: 10.1007/BF00174867.
3
Evidence for saturation of catechol-O-methyltransferase by low concentrations of noradrenaline in perfused lungs of rats.低浓度去甲肾上腺素使大鼠灌注肺中儿茶酚-O-甲基转移酶饱和的证据。
Naunyn Schmiedebergs Arch Pharmacol. 1995 Apr;351(4):408-16. doi: 10.1007/BF00169082.
4
The activity of the neuronal and extraneuronal catecholamine-metabolizing enzymes of the perfused rat heart.灌注大鼠心脏的神经元和非神经元儿茶酚胺代谢酶的活性
Naunyn Schmiedebergs Arch Pharmacol. 1987 Aug;336(2):139-47. doi: 10.1007/BF00165797.
5
The neuronal and extraneuronal uptake and metabolism of 3H-(-)-noradrenaline in the perfused rat heart.灌注大鼠心脏中3H-（-）-去甲肾上腺素的神经元和非神经元摄取及代谢
Naunyn Schmiedebergs Arch Pharmacol. 1978 May;303(1):21-35. doi: 10.1007/BF00496182.
6
Kinetics of norepinephrine metabolism in the rat heart in vivo.大鼠心脏去甲肾上腺素代谢的体内动力学
Biochem Pharmacol. 1974 Feb 1;23(3):697-703. doi: 10.1016/0006-2952(74)90634-0.
7
Metabolism of centrally released noradrenaline by extraneuronal monoamine oxidase and catechol-O-methyltransferase.中枢释放的去甲肾上腺素在外周单胺氧化酶和儿茶酚-O-甲基转移酶作用下的代谢
Brain Res. 1976 Apr 23;106(2):403-6. doi: 10.1016/0006-8993(76)91037-4.
8
The substrate specificity of uptake2 in the rat heart.大鼠心脏中摄取2的底物特异性。
Naunyn Schmiedebergs Arch Pharmacol. 1984 Dec;328(2):164-73. doi: 10.1007/BF00512067.
9
Mechanisms of the release of 3H-noradrenaline by dimethylphenylpiperazinium (DMPP) in the rat vas deferens.大鼠输精管中二甲苯基哌嗪（DMPP）释放3H-去甲肾上腺素的机制。
Naunyn Schmiedebergs Arch Pharmacol. 1990 Jan-Feb;341(1-2):43-9. doi: 10.1007/BF00195056.
10
The handling of five amines by the extraneuronal deaminating system of the rat heart.大鼠心脏非神经元脱氨基系统对五种胺类的处理
Naunyn Schmiedebergs Arch Pharmacol. 1988 Feb;337(2):159-63. doi: 10.1007/BF00169243.

引用本文的文献

1
Affinities of catecholamines for extraneuronal uptake in smooth muscle cells in trachealis muscle of guinea-pig.儿茶酚胺对豚鼠气管平滑肌细胞非神经元摄取的亲和力。
Naunyn Schmiedebergs Arch Pharmacol. 1980 Mar;311(2):139-46. doi: 10.1007/BF00510252.
2
A mathematical model representing the extraneuronal O-methylating system of the perfused rat heart.一种代表灌注大鼠心脏细胞外O-甲基化系统的数学模型。
Naunyn Schmiedebergs Arch Pharmacol. 1980 Feb;311(1):17-32. doi: 10.1007/BF00500298.
3
The positive inotropic effect of (-)-noradrenaline and (+/-)-isoprenaline after chemical sympathectomy: evidence in favour of differences at a postsynaptic site.

本文引用的文献

1
The uptake of catechol amines at high perfusion concentrations in the rat isolated heart: A novel catechol amine uptake process.大鼠离体心脏在高灌注浓度下对儿茶酚胺的摄取：一种新的儿茶酚胺摄取过程。
Br J Pharmacol Chemother. 1965 Aug;25(1):18-33. doi: 10.1111/j.1476-5381.1965.tb01753.x.
2
Statistical estimations in enzyme kinetics.酶动力学中的统计估计
Biochem J. 1961 Aug;80(2):324-32. doi: 10.1042/bj0800324.
3
The uptake of isoprenaline and noradrenaline by the perfused rat heart.灌流大鼠心脏对异丙肾上腺素和去甲肾上腺素的摄取
化学性交感神经切除术后（-）-去甲肾上腺素和（±）-异丙肾上腺素的正性肌力作用：支持突触后位点存在差异的证据。
Naunyn Schmiedebergs Arch Pharmacol. 1981 Feb;316(1):8-18. doi: 10.1007/BF00507220.
4
The neuronal and extraneuronal uptake and deamination of 3H-(-)-phenylephrine in the perfused rat heart.
Naunyn Schmiedebergs Arch Pharmacol. 1980 Nov;314(3):237-47. doi: 10.1007/BF00498545.
5
The cellular location of catechol-O-methyltransferase in rat liver.大鼠肝脏中儿茶酚-O-甲基转移酶的细胞定位。
Naunyn Schmiedebergs Arch Pharmacol. 1982 Aug;320(2):182-8. doi: 10.1007/BF00506319.
6
The isotope effect of tritium in 3H-noradrenaline.3H-去甲肾上腺素中氚的同位素效应。
Naunyn Schmiedebergs Arch Pharmacol. 1983 Jun;323(2):128-40. doi: 10.1007/BF00634260.
7
A comparative study of the properties of the catechol-O-methyltransferase inhibitors, U-0521 and tropolone acetamide, in rat perfused heart.大鼠离体灌流心脏中儿茶酚-O-甲基转移酶抑制剂U-0521与托酚酮乙酰胺性质的比较研究
Naunyn Schmiedebergs Arch Pharmacol. 1983 Feb;322(1):6-19. doi: 10.1007/BF00649346.
8
The substrate specificity of uptake2 in the rat heart.大鼠心脏中摄取2的底物特异性。
Naunyn Schmiedebergs Arch Pharmacol. 1984 Dec;328(2):164-73. doi: 10.1007/BF00512067.
9
Kinetics of the O-methylating system for isoprenaline in the trachea and aorta of rabbit.兔气管和主动脉中异丙肾上腺素O-甲基化系统的动力学
Naunyn Schmiedebergs Arch Pharmacol. 1984 Nov;328(1):56-61. doi: 10.1007/BF00496107.
10
The influence of inhibition of catechol-O-methyl transferase or of monoamine oxidase on the extraneuronal metabolism of 3H-(-)-noradrenaline in the rat heart.儿茶酚-O-甲基转移酶抑制或单胺氧化酶抑制对大鼠心脏中3H-(-)-去甲肾上腺素细胞外代谢的影响。
Naunyn Schmiedebergs Arch Pharmacol. 1984 Oct;327(4):285-92. doi: 10.1007/BF00506238.
Mol Pharmacol. 1966 Jan;2(1):37-42.
4
Histochemical studies on the uptake of noradrenaline in the perfused rat heart.灌注大鼠心脏中去甲肾上腺素摄取的组织化学研究。
Br J Pharmacol. 1968 Sep;34(1):227P-228P.
5
Species and tissue variation in extraneuronal and neuronal accumulation of noradrenaline.去甲肾上腺素在非神经元和神经元中的蓄积的物种及组织差异。
J Physiol. 1970 Mar;206(3):591-604. doi: 10.1113/jphysiol.1970.sp009032.
6
Adrenergic receptors in heart muscle: relations among factors influencing the sensitivity of the cat papillary muscle to catecholamines.心肌中的肾上腺素能受体：影响猫乳头肌对儿茶酚胺敏感性的因素之间的关系。
J Pharmacol Exp Ther. 1970 Jun;173(2):383-98.
7
The role of uptake2 in the extraneuronal metabolism of catecholamines in the isolated rat heart.摄取2在离体大鼠心脏儿茶酚胺的非神经元代谢中的作用。
Br J Pharmacol. 1969 Nov;37(3):638-49. doi: 10.1111/j.1476-5381.1969.tb08502.x.
8
Preferential metabolism of (-) 3 H-norepinephrine through the deaminated glycol in the rat vas deferens.大鼠输精管中（-）3H-去甲肾上腺素通过脱氨基二醇的优先代谢。
Biochem Pharmacol. 1973 May 15;22(10):1147-60. doi: 10.1016/0006-2952(73)90231-1.
9
The effect of hydrocortisone on the sensitivity of the isolated nictitating membrane to catecholamines: Relationship to extraneuronal uptake and metabolism.氢化可的松对离体瞬膜对儿茶酚胺敏感性的影响：与神经外摄取及代谢的关系。
Naunyn Schmiedebergs Arch Pharmacol. 1974;286(1):1-48. doi: 10.1007/BF00499103.
10
Extraneuronal removal, accumulation and O-methylation of isoprenaline in the perfused heart.灌注心脏中异丙肾上腺素的非神经元性清除、蓄积及O-甲基化作用
Naunyn Schmiedebergs Arch Pharmacol. 1974;283(2):191-218. doi: 10.1007/BF00501145.