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[脓毒性休克时血液流变学特性的变化]

[Changes in the rheologic properties of blood in septic shock].

作者信息

Radzivil G G, Minsker G D

出版信息

Vestn Khir Im I I Grek. 1984 Apr;132(4):19-25.

PMID:6730174
Abstract

Results of examination of rheological properties of blood in 62 patients with septic shock of peritoneal etiology are presented. The control group included 50 patients with diffuse peritonitis without manifestations of septic shock. In patients with favourable outcomes of the disease septic shock was accompanied by the development of the high blood viscosity syndrome of the IInd degree or low blood viscosity syndrome of the Ist degree when microcirculatory and thrombohemorrhagic complications were of a reversible character. Irreversible septic shock was associated with the low blood viscosity syndrome of the IInd degree with a developing hypocoagulopathy of consumption when the therapeutic methods failed to correct rheological and microcirculatory disorders. Attention is called to differentiated approach to the treatment with special reference to the degree and phase of the rheological disorders.

摘要

本文呈现了62例腹膜源性脓毒症休克患者血液流变学特性的检查结果。对照组包括50例无脓毒症休克表现的弥漫性腹膜炎患者。疾病转归良好的患者,脓毒症休克伴有Ⅱ度高血粘度综合征或Ⅰ度低血粘度综合征的发生,此时微循环和血栓出血性并发症具有可逆性。不可逆性脓毒症休克与Ⅱ度低血粘度综合征相关,伴有消耗性低凝血病的发展,此时治疗方法未能纠正血液流变学和微循环紊乱。文中呼吁在治疗时应采取差异化方法,尤其要关注血液流变学紊乱的程度和阶段。

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