Simeonov P, Todorov V, Baldev Ts, Todorov K, Patev E
Vutr Boles. 1984;23(1):40-6.
Fifty three patients with programmed hemodialysis, in a stable state were studied to the method of urea-kinetic modelling. A high correlation relationship was established between the pre-dialysis values of urea nitrogen in blood and the protein import, calculated from the quantity of the endogenously produced urea nitrogen. The best rehabilitated patients (41,5%) proved to introduce 1,0-1,6 g/kg body weight proteins and maintain a concentration of blood urea nitrogen from 65-95 ng% (32,14-33,8 mmol/1). Furthermore, another three patient groups were formed: with reduced protein introduction, with insufficient clearance and with overnormal protein introduction. The optimal group significantly differ from them, according to the state of nourishment, general rehabilitation, phosphatemia, calcium-phosphorus number and dialysis clearance. Both the stage of anemia and arterial hypertension show only a tendency in similar direction.
对53例处于稳定状态的进行程序性血液透析的患者进行了尿素动力学建模方法的研究。血液中尿素氮的透析前值与根据内源性产生的尿素氮量计算出的蛋白质摄入量之间建立了高度相关关系。康复效果最佳的患者(41.5%)被证明摄入1.0 - 1.6克/千克体重的蛋白质,并将血尿素氮浓度维持在65 - 95纳克%(32.14 - 33.8毫摩尔/升)。此外,还形成了另外三组患者:蛋白质摄入量减少组、清除不足组和蛋白质摄入量超常组。根据营养状况、总体康复情况、血磷、钙磷指数和透析清除率,最佳组与他们有显著差异。贫血阶段和动脉高血压阶段仅显示出相似方向的趋势。