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[计划性血液透析患者的尿素动力学模型]

[Urea kinetics model of patients on programmed hemodialysis].

作者信息

Simeonov P, Todorov V, Baldev Ts, Todorov K, Patev E

出版信息

Vutr Boles. 1984;23(1):40-6.

PMID:6730449
Abstract

Fifty three patients with programmed hemodialysis, in a stable state were studied to the method of urea-kinetic modelling. A high correlation relationship was established between the pre-dialysis values of urea nitrogen in blood and the protein import, calculated from the quantity of the endogenously produced urea nitrogen. The best rehabilitated patients (41,5%) proved to introduce 1,0-1,6 g/kg body weight proteins and maintain a concentration of blood urea nitrogen from 65-95 ng% (32,14-33,8 mmol/1). Furthermore, another three patient groups were formed: with reduced protein introduction, with insufficient clearance and with overnormal protein introduction. The optimal group significantly differ from them, according to the state of nourishment, general rehabilitation, phosphatemia, calcium-phosphorus number and dialysis clearance. Both the stage of anemia and arterial hypertension show only a tendency in similar direction.

摘要

对53例处于稳定状态的进行程序性血液透析的患者进行了尿素动力学建模方法的研究。血液中尿素氮的透析前值与根据内源性产生的尿素氮量计算出的蛋白质摄入量之间建立了高度相关关系。康复效果最佳的患者(41.5%)被证明摄入1.0 - 1.6克/千克体重的蛋白质,并将血尿素氮浓度维持在65 - 95纳克%(32.14 - 33.8毫摩尔/升)。此外,还形成了另外三组患者:蛋白质摄入量减少组、清除不足组和蛋白质摄入量超常组。根据营养状况、总体康复情况、血磷、钙磷指数和透析清除率,最佳组与他们有显著差异。贫血阶段和动脉高血压阶段仅显示出相似方向的趋势。

相似文献

1
[Urea kinetics model of patients on programmed hemodialysis].[计划性血液透析患者的尿素动力学模型]
Vutr Boles. 1984;23(1):40-6.
2
[Estimation of the dialysis time based on a simplified algorithm for urea kinetics].[基于尿素动力学简化算法的透析时间估算]
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3
Simple and accurate quantification of dialysis in acute renal failure patients during either urea non-steady state or treatment with irregular or continuous schedules.在尿素非稳态期间或采用不规则或持续透析方案治疗急性肾衰竭患者时,对透析进行简单而准确的量化。
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4
Adequacy of hemodialysis.血液透析充分性
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Clin Nephrol. 1997 Jun;47(6):379-83.
6
A new algorithm for individual dialysis prescription based on urea kinetics.一种基于尿素动力学的个体化透析处方新算法。
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7
Effects of different sampling methods for measurement of post dialysis blood urea nitrogen on urea kinetic modeling derived parameters in patients undergoing long-term hemodialysis.
ASAIO J. 1995 Apr-Jun;41(2):211-5.
8
Urea kinetics and dialysis treatment time predict vancomycin elimination during high-flux hemodialysis.尿素动力学和透析治疗时间可预测高通量血液透析期间万古霉素的清除情况。
Clin Pharmacol Ther. 1998 Jan;63(1):26-38. doi: 10.1016/S0009-9236(98)90118-7.
9
Is urea kinetic modelling an appropriate tool for guiding ultrashort high-flux dialysis therapy?尿素动力学建模是否是指导超短高通量透析治疗的合适工具?
Nephrol Dial Transplant. 1991;6 Suppl 3:86-7.
10
Prescribing hemodialysis using a nomogram approach to urea kinetic modelling.采用列线图法进行尿素动力学建模来开具血液透析处方。
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