Vakov L
Vutr Boles. 1984;23(1):79-84.
Blood serotonin was determined in 184 patients with diabetes mellitus by a biological method. Its average value in diabetics was significantly lower than that of the control healthy subjects. The changes established show a light dependence on sex and age of the patients, duration and type of the disease, blood sugar level and the kind of drug treatment. They are better manifested in the presence of retinopathy versus in its absence, as well as in the presence of proliferative versus non-proliferative one. With the compensation of the diabetes, a tendency to partial normalization of serotonin blood level was observed. The probable causes of serotonin changes established are discussed.
采用生物学方法对184例糖尿病患者的血液血清素进行了测定。糖尿病患者血清素的平均值显著低于健康对照者。所发现的变化显示出对患者的性别、年龄、疾病持续时间和类型、血糖水平以及药物治疗种类的轻度依赖。与无视网膜病变相比，视网膜病变患者的变化更明显，增殖性视网膜病变患者与非增殖性视网膜病变患者相比也是如此。随着糖尿病得到代偿，观察到血清素血液水平有部分恢复正常的趋势。文中讨论了所发现的血清素变化的可能原因。
