Körfer R, Bircks W, Frilling A, Horstkotte D, Meyer H, Minami K, Schulte H D
Z Kardiol. 1984 Apr;73(4):269-72.
In the period between 1955 and 1982, 297 patients underwent surgical correction of a partial AV-canal. Closure of the ostium primum defect was performed either by direct suture or by patch (prosthetic material or pericardium). Only in cases with severe mitral incompetence was the cleft in the anterior leaflet of the mitral valve surgically treated. At an average of 6 years (range: 3 months - 22 years) after the initial procedure 21 patients (7.8 per cent) underwent reoperation. In 20 patients reoperation was necessary for hemodynamic reasons (recurrence of ASD: n = 8; severe AV-valve regurgitation: n = 3; or both: n = 9). One patient with moderate mitral valve incompetence suffered from severe "patch-hemolysis" due to direction of the blood-jet towards the prosthetic patch. Residual or recurrent atrial septal defects were closed by using a patch in cases with previous direct suture (39 patients - 8 reoperations) or by reinsertion or enlargement of the present patch (258 patients - 13 reoperations). AV-valve incompetence could be treated in all cases but two with reconstructive methods. In two patients implantation of a prosthetic valve was necessary. In the single case with "patch-hemolysis" the previous prosthetic patch was replaced by a pericardial one, together with a suture of the mitral cleft 3 months after operation. Mortality of reoperation was 14.5 per cent (3 early deaths). Major complications in the surviving patients did not occur, with one exception: one patient with postoperative total AV-block received a permanent pacemaker.
在1955年至1982年期间,297例患者接受了部分房室通道的手术矫正。原发孔缺损的闭合采用直接缝合或补片(人工材料或心包)。仅在严重二尖瓣关闭不全的病例中,对二尖瓣前叶的裂隙进行手术治疗。初次手术后平均6年(范围:3个月至22年),21例患者(7.8%)接受了再次手术。20例患者因血流动力学原因需要再次手术(房间隔缺损复发:8例;严重房室瓣反流:3例;或两者皆有:9例)。1例中度二尖瓣关闭不全患者因血流喷射朝向人工补片而出现严重的“补片溶血”。对于先前采用直接缝合的病例(39例患者 - 8例再次手术),残留或复发性房间隔缺损通过使用补片进行闭合;对于其余病例(258例患者 - 13例再次手术),则通过重新植入或扩大现有补片进行闭合。除两例外,所有病例的房室瓣关闭不全均可用重建方法治疗。2例患者需要植入人工瓣膜。在“补片溶血”的唯一病例中,术后3个月将先前的人工补片更换为心包补片,并对二尖瓣裂隙进行缝合。再次手术的死亡率为14.5%(3例早期死亡)。存活患者未发生重大并发症,但有一例除外:一名术后发生完全性房室传导阻滞的患者接受了永久性起搏器植入。