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[不同年龄大鼠离体灌注肝脏的吞噬活性。用铜蓝蛋白灌注后的生化与结构研究]

[Phagocytic activity of isolated perfused liver of rats of different ages. Biochemical and structural studies following perfusion with Cu-ceruloplasmin].

作者信息

Vömel T, Platt D, Schnorr B

出版信息

Z Gerontol. 1984 Mar-Apr;17(2):69-72.

PMID:6730634
Abstract

The phagocytic activity of young and old isolated perfused rat livers was measured referred to a glycoprotein (Cu-coeruloplasmin). It was shown that the phagocytic activity of the old rat liver is significantly higher than that of the young rat liver. There was no age-dependent difference of the parameters of liver function GOT, GPT, Kt and the quotients beta-OH-Butyric acid/Acetoacetate and lactate/butyrate.

摘要

以一种糖蛋白(铜蓝蛋白)为参照,测定了幼年和老年大鼠离体灌注肝脏的吞噬活性。结果表明,老年大鼠肝脏的吞噬活性显著高于幼年大鼠肝脏。肝功能指标谷草转氨酶(GOT)、谷丙转氨酶(GPT)、Kt以及β-羟基丁酸/乙酰乙酸和乳酸/丁酸的比值不存在年龄依赖性差异。

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