Volynkina G Iu, Krylov I N
Zh Nevropatol Psikhiatr Im S S Korsakova. 1984;84(4):596-600.
The components of the startle reaction (SR) (reactions of nonspecific motor activation, the wink reflex and reflectory alleviation of motoneurones) were utilized as indices of the functional status of the midbrain system of cerebral nonspecific activation. Healthy subjects and chronic alcoholics in the abstinence period were examined. The patients exhibited significantly lower SR thresholds, a shortened latent period and a stronger reaction as compared with the healthy subjects which was suggestive of the irritation of the mesencephalic activating mechanisms in patients during the period of abstinence. Intake of the euphorizing doses of ethanol depressed the acoustic SR in both patients and controls. It is concluded that ethanol exerts an inhibitory action on the midbrain system of brain nonspecific activation.
惊吓反应（SR）的组成部分（非特异性运动激活反应、眨眼反射和运动神经元的反射性减轻）被用作大脑非特异性激活中脑系统功能状态的指标。对健康受试者和戒酒期的慢性酒精中毒者进行了检查。与健康受试者相比，患者表现出明显更低的SR阈值、更短的潜伏期和更强的反应，这表明在戒酒期患者的中脑激活机制受到了刺激。给予能产生欣快感剂量的乙醇会抑制患者和对照组的听觉SR。得出的结论是，乙醇对大脑非特异性激活的中脑系统具有抑制作用。
