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人类孕期正常及异常的催乳素水平。对胎儿-胎盘内分泌功能无影响。

Normal and abnormal prolactin levels during human pregnancy. Lack of influence on fetoplacental endocrine function.

作者信息

Andersen A N, Pedersen H, Westergaard J G, Schiøler V, Arends J

出版信息

Acta Obstet Gynecol Scand. 1984;63(2):145-8. doi: 10.3109/00016348409154650.

DOI:10.3109/00016348409154650
PMID:6730928
Abstract

Serial measurements of serum prolactin (PRL), chorionic gonadotropin (hCG), estradiol and progesterone were performed during 16 normal pregnancies. The same hormone analyses were performed in a woman with the galactorrhea-amenorrhea syndrome and a pituitary adenoma during two pregnancies, with and without continued treatment with bromocriptine throughout gestation. The study indicates that marked differences in circulating PRL levels do not influence the fetoplacental hormone levels. Furthermore, tumor expansion may possibly be prevented and successful breast-feeding can be achieved after treatment with bromocriptine throughout gestation.

摘要

在16例正常妊娠期间对血清催乳素(PRL)、绒毛膜促性腺激素(hCG)、雌二醇和孕酮进行了连续测定。对一名患有溢乳-闭经综合征和垂体腺瘤的女性在两次妊娠期间进行了同样的激素分析,一次是在整个妊娠期持续使用溴隐亭治疗,另一次则未使用。该研究表明,循环PRL水平的显著差异不会影响胎盘-胎儿激素水平。此外,在整个妊娠期使用溴隐亭治疗后,可能会预防肿瘤扩大,并实现成功哺乳。

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1
Normal and abnormal prolactin levels during human pregnancy. Lack of influence on fetoplacental endocrine function.人类孕期正常及异常的催乳素水平。对胎儿-胎盘内分泌功能无影响。
Acta Obstet Gynecol Scand. 1984;63(2):145-8. doi: 10.3109/00016348409154650.
2
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Am J Obstet Gynecol. 1982 Mar 15;142(6 Pt 1):634-9. doi: 10.1016/s0002-9378(16)32432-2.
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Acute changes in serum prolactin concentration have no effect on the secretion of progesterone, estradiol, or chorionic gonadotropin during early pregnancy.在妊娠早期,血清催乳素浓度的急性变化对孕酮、雌二醇或绒毛膜促性腺激素的分泌没有影响。
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