Assev S, Rölla G
Acta Pathol Microbiol Immunol Scand B. 1984 Apr;92(2):89-92. doi: 10.1111/j.1699-0463.1984.tb02800.x.
A cariogenic bacterial strain, Streptococcus mutans OMZ 176, was found to be able to take up xylitol by a phosphotransferase system (pts) in spite of lack of ability to catabolize this pentitol. A metabolite with an Rf value in TLC similar to xylitol 5-phosphate was extracted from resting cells which had been exposed to 14C xylitol. Phosphatase treatment of this metabolite yielded xylitol. It is suggested that the inhibition of growth of Strep. mutans observed in several laboratories can be explained in terms of accumulation of xylitol phosphate (presumably xylitol 5-phosphate) inside the cells. It is furthermore suggested that xylitol is transported and phosphorylated through the fructose pts.
一种致龋菌株——变形链球菌OMZ 176，尽管缺乏分解这种戊糖醇的能力，但被发现能够通过磷酸转移酶系统（pts）摄取木糖醇。从暴露于14C木糖醇的静息细胞中提取出一种在薄层色谱（TLC）中Rf值与5-磷酸木糖醇相似的代谢物。对该代谢物进行磷酸酶处理后产生了木糖醇。有人提出，在几个实验室中观察到的变形链球菌生长抑制现象，可以用细胞内磷酸木糖醇（可能是5-磷酸木糖醇）的积累来解释。此外，有人提出木糖醇是通过果糖pts进行转运和磷酸化的。
