正常情况下以及在输注异丙肾上腺素和多巴酚丁胺期间心肌葡萄糖消耗的分布情况。
Distribution of myocardial glucose consumption under normal conditions and during isoprenaline and dobutamine infusion.
作者信息
Breull W, Rubart M
出版信息
Adv Exp Med Biol. 1984;169:369-80. doi: 10.1007/978-1-4684-1188-1_32.
The regional myocardial metabolic rate of glucose (reg. MMR Gl) of the left ventricular free wall was determined applying the 2-deoxyglucose method (Sokoloff, 1977) in the anesthetized closed chest dog. Under control conditions an inhomogeneous distribution of MMR Gl was observed. Isoprenaline or dobutamine infusions resulted in a redistribution of MMR Gl. With isoprenaline a homogeneous distribution pattern was observed, while with dobutamine a slight decrease in MMR Gl of the subendocardial region was measured. This redistribution may result from altered ventricular working conditions, due to changes in ventricular volumes or from differences in the frequency of myocardial adrenoceptors within the ventricular wall.
采用2-脱氧葡萄糖法（索科洛夫，1977年）在麻醉开胸犬身上测定左心室游离壁局部心肌葡萄糖代谢率（reg. MMR Gl）。在对照条件下，观察到MMR Gl分布不均匀。输注异丙肾上腺素或多巴酚丁胺导致MMR Gl重新分布。使用异丙肾上腺素时，观察到均匀分布模式，而使用多巴酚丁胺时，测量到心内膜下区域的MMR Gl略有下降。这种重新分布可能是由于心室容积变化导致心室工作条件改变，或心室壁内心肌肾上腺素能受体频率差异所致。
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