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院外心脏性猝死后的长期生存情况。

Long-term survival after prehospital sudden cardiac death.

作者信息

Tresch D D, Keelan M H, Siegel R, Troup P J, Bonchek L I, Olinger G N, Brooks H L

出版信息

Am Heart J. 1984 Jul;108(1):1-5. doi: 10.1016/0002-8703(84)90536-2.

Abstract

One hundred thirty-nine survivors of prehospital sudden cardiac death were followed after their hospital discharge. Eighty patients were studied with coronary angiography and cardiac catheterization; 34 of these underwent coronary bypass surgery. After a maximum follow-up of 105 months, 89 patients were still alive. The probability of survival at 6 months, 1 year, 2 years, 3 years, 4 years, and 5 years was 88%, 86%, 78%, 70%, 63%, and 59%, respectively. Of the 43 cardiac deaths, 37 (86%) were secondary to documented recurrent ventricular fibrillation or occurred suddenly. Twelve percent of the total population had recurrent ventricular fibrillation in the first year following the initial cardiac arrest, 16% within 2 years, and 22% within 3 years. Of the 37 survivors dying from recurrent ventricular fibrillation, 32% died within the first 3 months following hospital discharge, 46% in the first year, 64% within 2 years, and 78% within the first 3 years. Most survivors were capable of resuming normal activities after hospital discharge. Only 7% demonstrated permanent neurologic impairment. Sixty-eight percent of the patients who were employed at the time of their prehospital sudden cardiac arrest returned to full-time employment. In the subset of 34 surgically treated patients, there have been six (18%) cardiac deaths. Four of these deaths were related to recurrent ventricular fibrillation, with one of these deaths occurring in the immediate postoperative period. The other three deaths related to recurrent ventricular fibrillation occurred 36 months (two deaths) and 49 months following the initial prehospital cardiac arrest.

摘要

139例院外心脏骤停幸存者在出院后接受了随访。80例患者接受了冠状动脉造影和心导管检查;其中34例接受了冠状动脉搭桥手术。在最长105个月的随访后,89例患者仍然存活。6个月、1年、2年、3年、4年和5年的生存率分别为88%、86%、78%、70%、63%和59%。在43例心源性死亡病例中,37例(86%)继发于记录在案的复发性室颤或猝死。在初始心脏骤停后的第一年,总人口中有12%发生复发性室颤,2年内为16%,3年内为22%。在37例死于复发性室颤的幸存者中,32%在出院后的前3个月内死亡,46%在第一年内死亡,64%在2年内死亡,78%在最初3年内死亡。大多数幸存者出院后能够恢复正常活动。只有7%表现出永久性神经功能损害。在院外心脏骤停发生时就业的患者中,68%恢复了全职工作。在34例接受手术治疗的患者亚组中,有6例(18%)发生心源性死亡。其中4例死亡与复发性室颤有关,其中1例死亡发生在术后即刻。另外3例与复发性室颤相关的死亡发生在初始院外心脏骤停后的36个月(2例死亡)和49个月。

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