Fischer P R, Gooch W M, Walker M L, Storrs B
Antimicrob Agents Chemother. 1984 Apr;25(4):502-3. doi: 10.1128/AAC.25.4.502.
After a 1-h exposure to concentrations used for topical prophylaxis in neurosurgical procedures, bacitracin, vancomycin, and oxacillin were bactericidal against more than 90% of 48 body fluid isolates of coagulase-negative staphylococci. More than 10% of isolates survived despite exposure for 4 h to concentrations of gentamicin and streptomycin greater than those employed for topical prophylaxis.
在暴露于神经外科手术局部预防所用浓度1小时后，杆菌肽、万古霉素和苯唑西林对48株凝固酶阴性葡萄球菌的体液分离株中的90%以上具有杀菌作用。尽管暴露于高于局部预防所用浓度的庆大霉素和链霉素4小时，但仍有超过10%的分离株存活。
