Sade R M, Crawford F A, Hohn A R, Riopel D A, Taylor A B
Ann Thorac Surg. 1984 Jul;38(1):21-5. doi: 10.1016/s0003-4975(10)62179-0.
We have shown that patch aortoplasty relieves the aortic pressure gradient substantially better than resection with end-to-end anastomosis in infants with coarctation of the aorta. Growth of the intact posterior wall of the unresected coarctation after aortoplasty, however, has not yet been demonstrated to occur. We studied 21 infants less than 2 years of age who underwent prosthetic patch repair of coarctation after 1975. Associated lesions were present in 16 patients, and 12 had a concomitant procedure. Two patients died in the hospital, and 4 died later, all of causes unrelated to the coarctation repair. Systolic blood pressure in the right arm declined from 140 +/- 41 mm Hg (mean +/- standard deviation) preoperatively to 101 +/- 19 mm Hg postoperatively in the whole group and to 95 +/- 12 in 10 patients followed for more than 3 years. The right arm-left leg systolic pressure gradient declined from 66 +/- 22 mm Hg to 5 +/- 14 in all patients and to 4 +/- 13 in the group followed more than 3 years. Hypoplastic transverse arch was seen in all but 2 patients. Its relative diameter increased in 6 of 9 patients who underwent catheterization postoperatively and increased more than 50% in 3 patients. Two patients have evidence of narrowing of the aorta at the patch, but both have normal blood pressure in the right arm. In the patient with longest follow-up, an 8-month-old infant seen 8 years after operation, angiograms show the diameter of the aorta at the coarctation to be greater than that at the transverse arch and at the descending aorta.(ABSTRACT TRUNCATED AT 250 WORDS)
我们已经表明,在患有主动脉缩窄的婴儿中,补片主动脉成形术比端对端吻合切除术能更好地缓解主动脉压力梯度。然而,主动脉成形术后未切除的缩窄部位完整后壁的生长情况尚未得到证实。我们研究了1975年后接受人工补片修复主动脉缩窄的21例2岁以下婴儿。16例患者存在相关病变,12例进行了同期手术。2例患者在医院死亡,4例后来死亡,所有死亡原因均与主动脉缩窄修复无关。全组患者右臂收缩压术前为140±41 mmHg(均值±标准差),术后降至101±19 mmHg,10例随访超过3年的患者降至95±12 mmHg。所有患者右臂与左腿收缩压梯度从66±22 mmHg降至5±14 mmHg,随访超过3年的组降至4±13 mmHg。除2例患者外,所有患者均可见发育不良的横弓。9例术后接受心导管检查的患者中有6例其相对直径增加,3例增加超过50%。2例患者有补片处主动脉狭窄的证据,但右臂血压均正常。在随访时间最长的患者(一名8个月大婴儿,术后8年接受检查)中,血管造影显示缩窄部位的主动脉直径大于横弓和降主动脉处的直径。(摘要截取自250字)