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主动脉缩窄。采用聚四氟乙烯补片主动脉成形术进行修复。

Coarctation of the aorta. Repair with polytetrafluoroethylene patch aortoplasty.

作者信息

Backer C L, Paape K, Zales V R, Weigel T J, Mavroudis C

机构信息

Division of Cardiovascular-Thoracic Surgery, Children's Memorial Hospital, Chicago, IL 60614, USA.

出版信息

Circulation. 1995 Nov 1;92(9 Suppl):II132-6. doi: 10.1161/01.cir.92.9.132.

Abstract

BACKGROUND

The first successful surgical repair of coarctation of the aorta (CoAo) was performed in 1944, but during the years that followed a high incidence of recoarctation was seen, ranging from 20% to 86%. In response to that problem, the patch aortoplasty was introduced in 1957; however, true aneurysms were found in the aortic wall opposite the patch after Dacron patch aortoplasty, particularly when the coarctation ridge was excised. The purpose of our review was to evaluate the results of patch aortoplasty for CoAo using a relatively new material, polytetrafluoroethylene (PTFE), and an operative technique that does not involve resection of the coarctation ridge.

METHODS AND RESULTS

Between 1979 and 1993, 125 infants and children underwent PTFE patch aortoplasty for CoAo; 111 of the procedures were primary repairs, and 14 were reoperations. Diagnoses were isolated CoAo (96 patients), CoAo and ventricular septal defect (15 patients), and CoAo with complex intracardiac anomaly (14 patients). Patient age at the time of repair ranged from 4 days to 17 years (mean age, 5.1 +/- 4.5 years). There were no instances of intraoperative mortality or paraplegia. There were 4 deaths from 10 to 40 days postoperatively, all in neonates (mean age, 33 days) who received additional intracardiac procedures for complex associated anomalies. Follow-up has ranged from 6 months to 12.5 years (mean, 4.5 +/- 3.2 years). All children had postoperative chest roentgenograms, 80 (66%) patients have had a postoperative echocardiogram and 16 (13%) a cardiac catheterization. One patient had successful repair of a false aneurysm 4 months postoperatively. No patient has developed a late true aneurysm. Of the patients < 1 month of age at the time of CoAo repair (12 patients), 6 patients had recurrent CoAo (gradient > 20 mm Hg) compared with only 4 recurrences in 97 patients > 1 month of age at the time of repair (P < .001).

CONCLUSIONS

For children > 1 year of age, PTFE patch aortoplasty remains our procedure of choice for CoAo repair because of the low mortality rate, low recoarctation rate, and absence of late true aneurysms. We have stopped using this technique for infants < 1 month of age because of the high recurrence rate.

摘要

背景

1944年首次成功实施了主动脉缩窄(CoAo)的外科修复手术,但在随后的几年中,再缩窄的发生率很高,范围在20%至86%之间。针对这一问题,1957年引入了补片主动脉成形术;然而,在涤纶补片主动脉成形术后,在补片相对的主动脉壁发现了真性动脉瘤,尤其是在切除缩窄嵴时。我们综述的目的是评估使用一种相对较新的材料聚四氟乙烯(PTFE)以及不涉及切除缩窄嵴的手术技术进行CoAo补片主动脉成形术的结果。

方法和结果

1979年至1993年期间,125例婴儿和儿童接受了CoAo的PTFE补片主动脉成形术;其中111例手术为初次修复,14例为再次手术。诊断包括孤立性CoAo(96例患者)、CoAo合并室间隔缺损(15例患者)以及CoAo合并复杂心内畸形(14例患者)。修复时患者年龄范围为4天至17岁(平均年龄5.1±4.5岁)。术中无死亡或截瘫病例。术后10至40天有4例死亡,均为新生儿(平均年龄33天),他们因复杂的相关畸形接受了额外的心内手术。随访时间为6个月至12.5年(平均4.5±3.2年)。所有儿童均进行了术后胸部X线检查,80例(66%)患者进行了术后超声心动图检查,16例(13%)进行了心导管检查。1例患者术后4个月成功修复了假性动脉瘤。无患者发生晚期真性动脉瘤。在CoAo修复时年龄<1个月的患者(12例)中,6例出现了再缩窄(压差>20 mmHg),而在修复时年龄>1个月的97例患者中只有4例复发(P<0.001)。

结论

对于1岁以上儿童,由于死亡率低、再缩窄率低且无晚期真性动脉瘤,PTFE补片主动脉成形术仍然是我们首选的CoAo修复手术方法。由于复发率高,我们已停止对1个月以下婴儿使用该技术。

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