Londino A V, Luparello F J
Arch Intern Med. 1984 Jul;144(7):1497-8.
A patient with factor XII deficiency, gout, and angioimmunoblastic lymphadenopathy (AIL) was seen initially for an acute myocardial infarction, gout, and unexplained urticaria. The patient eventually was found to have AIL and a prolonged partial thromboplastin time. There was no evidence of a circulating anticoagulant. A factor XII deficiency (Hageman factor) was discovered. The coexistence of a factor XII deficiency, AIL, and gout in the same person raises some interesting questions regarding the basic mechanisms of the inflammatory process.
一名患有因子Ⅻ缺乏症、痛风和血管免疫母细胞性淋巴结病（AIL）的患者最初因急性心肌梗死、痛风和不明原因的荨麻疹前来就诊。该患者最终被发现患有AIL且部分凝血活酶时间延长。没有循环抗凝剂的证据。发现了因子Ⅻ缺乏症（哈格曼因子）。同一人同时存在因子Ⅻ缺乏症、AIL和痛风，这就炎症过程的基本机制提出了一些有趣的问题。
