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锥杆营养不良患者的玻璃体荧光光度测定

Vitreous fluorophotometry in patients with cone-rod dystrophy.

作者信息

Miyake Y, Goto S, Ota I, Ichikawa H

出版信息

Br J Ophthalmol. 1984 Jul;68(7):489-93. doi: 10.1136/bjo.68.7.489.

Abstract

Eight patients with cone-rod dystrophy were examined by means of vitreous fluorophotometry. The data in three patients with an early stage of retinitis pigmentosa (rod-cone dystrophy) served for comparison. In contrast with the abnormal findings on vitreous fluorophotometry in patients with an early stage of retinitis pigmentosa the value of vitreous fluorophotometry in cone-rod dystrophy was within the normal range in all patients except the two with advanced stages of this disease. Our results suggest that, although both diseases are based on diffuse dystrophy of photoreceptors, and the final stages of the two diseases may show several similar features, the process of breakdown of the blood retinal barrier differs greatly in the two diseases.

摘要

对8例锥杆营养不良患者进行了玻璃体荧光光度测定检查。选取3例早期视网膜色素变性(杆锥营养不良)患者的数据作为对照。与早期视网膜色素变性患者玻璃体荧光光度测定的异常结果相反,除2例处于该疾病晚期的患者外,所有锥杆营养不良患者的玻璃体荧光光度测定值均在正常范围内。我们的结果表明,尽管这两种疾病均基于光感受器的弥漫性营养不良,且两种疾病的终末期可能表现出一些相似特征,但两种疾病中血视网膜屏障的破坏过程差异很大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59de/1040388/62f1f983d0b7/brjopthal00151-0066-a.jpg

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