鳗鲶壶腹电感受器中的阻尼振荡涉及受体细胞基底膜中钙激活的瞬时钾电导。
Damped oscillation in the ampullary electroreceptors of Plotosus involves Ca-activated transient K conductance in the basal membrane of receptor cells.
作者信息
Sugawara Y, Obara S
出版信息
Brain Res. 1984 Jun 4;302(1):171-5. doi: 10.1016/0006-8993(84)91296-4.
PMID:6733502
Abstract
K-blockers suppressed damped oscillation of Plotosus electroreceptors in situ. Ca-blockers abolished V-dependent non-linear responses, as well, and shifted the DC level in the ampulla by ca. -1 mV. Thus, the in situ receptor is held depolarized with maintained Ca current in the basal membrane of receptor cells. The oscillation involves Ca-activated transient K current in the same membrane, which contributes to the initial sensory adaptation, and presumably also to stabilizing the sensitive receptors.
摘要
钾通道阻滞剂抑制了斑鳍电感受器在原位的阻尼振荡。钙通道阻滞剂也消除了电压依赖性非线性反应，并使壶腹的直流水平大约下降了-1 mV。因此，原位感受器通过感受器细胞基底膜中持续的钙电流保持去极化状态。这种振荡涉及同一膜中的钙激活瞬时钾电流，该电流有助于初始感觉适应，并且可能也有助于稳定敏感的感受器。
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