Pascolini R, Tei S, Vagnetti D, Bondi C
Cell Tissue Res. 1984;236(2):345-9. doi: 10.1007/BF00214237.
The epidermal cells that migrate over the surface during the wound closure stage of head regeneration in Dugesia lugubris s.l. were examined by scanning electron microscopy. The effect of cytochalasin B on epidermal cell migration was also examined. During the first few hours after decapitation epidermal cells at the edges of the wound showed significant changes of shape related to the process of migration that was accomplished approximately 10 h after wounding. Flattening of the marginal cells was associated with active epidermal spreading throughout the healing period. Suitable support for migrating cells appeared to be a rhabditic network attached to the wound tissue. Epidermal cell migration was inhibited by cytochalasin B. These results demonstrate that the basis for cell movement in planarians is similar to that of many other systems.
用扫描电子显微镜检查了真涡虫属广义杜氏真涡虫头部再生伤口闭合阶段在伤口表面迁移的表皮细胞。还研究了细胞松弛素B对表皮细胞迁移的影响。断头后的最初几个小时内，伤口边缘的表皮细胞呈现出与迁移过程相关的显著形态变化，这种迁移过程在受伤后约10小时完成。边缘细胞的扁平化与整个愈合期表皮的积极扩展有关。迁移细胞的合适支撑似乎是附着在伤口组织上的杆状体网络。细胞松弛素B抑制了表皮细胞的迁移。这些结果表明，涡虫中细胞运动的基础与许多其他系统的相似。
